INTERFERON Α-INDUCIBLE PROTEIN 27 IS AN ONCOGENE AND HIGHLY EXPRESSED IN CHOLANGIOCARCINOMA PATIENTS WITH POOR SURVIVAL

Interferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival

Kun-Chun Chiang,1 Sheng-Teng Huang,2 Ren-Chin Wu,3 Shih-Chiang Huang,3 Ta-Sen Yeh,4 Ming-Huang Chen,5 Jun-Te Hsu,4 Li-Wei Chen,6 Sheng-Fong Kuo,7 Ho-Yen Chueh,8 Horng-Heng Juang,9 Shuen-Iu Hung,10 Chun-Nan Yeh,4 Jong-Hwei S Pang11,12 1General Surgery Department, Chang Gung Memorial Hospital, Chang Gung University, Keelung, Taiwan, ROC; 2Department

read more

Hypothermia and temperature modulation for intracerebral hemorrhage (ICH): pathophysiology and translational applications

BackgroundIntracerebral hemorrhage (ICH) still poses a substantial challenge in clinical medicine because of the high morbidity and mortality rate that characterizes it.This review article expands into the complex pathophysiological processes underlying primary and secondary neuronal death following ICH.It explores the potential of therapeutic hypo

read more

Intermediate filaments associate with aggresome-like structures in proteostressed C. elegans neurons and influence large vesicle extrusions as exophers

Abstract Toxic protein aggregates can spread among neurons to promote human neurodegenerative disease pathology.We found that in C.elegans touch neurons YOUNG AGAIN RINSE intermediate filament proteins IFD-1 and IFD-2 associate with aggresome-like organelles and are required cell-autonomously for efficient production of neuronal exophers, giant ves

read more

Internal auditor competence and internal control: Improving internal audit quality to prevent fraudulent financial statements

State-Owned Enterprises (BUMNs) YOUNG AGAIN RINSE in Indonesia are faced with challenges due to the weak prevention of fraudulent financial statements.The prevention of fraudulent financial statements has long been a subject of discussion.Therefore, this study aimed to investigate the relationship between internal auditor competence, internal contr

read more